In this issue of \u003ci\u003eClinics in Liver Disease\u003c/i\u003e, guest editor Dr. Mitchell L. Shiffman brings his considerable expertise to the topic of \u003cb\u003eNavigating the Management of Hepatocellular Carcinoma\u003c/b\u003e. Incidence rates of hepatocellular carcinoma (HCC) have more than tripled since 1980, and death rates have more than doubled during this time. This issue addresses diagnosis, treatment modalities, and surveillanceâall with real-world approaches. Selected articles include case histories, revealing how and why decisions were made.\u003cul\u003e\u003cli\u003eContains \u003cb\u003e12 relevant, practice-oriented topics\u003c/b\u003e including diagnosis and staging of HCC; real-world management of HCC: selected case presentations highlighting the dilemmas of surveillance; systemic therapy for HCC; real-world management of HCC: selected case presentations and how treatment decisions are made; management of chronic liver disease in patients with HCC; and more.\u003c/li\u003e\u003cli\u003eProvides in-depth \u003cb\u003eclinical reviews on the management of hepatocellular carcinoma\u003c/b\u003e, offering actionable insights for clinical practice.\u003c/li\u003e\u003cli\u003ePresents the \u003cb\u003elatest information on this timely, focused topic\u003c/b\u003e under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews\u003c/li\u003e\u003c/ul\u003e
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