Inhoudsopgave:
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\u003cp\u003e\u003ci\u003eXenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology\u003c/i\u003e covers the translational toxicology of xenobiotics substances in carcinogenesis by explaining the toxicokinetic and toxicodynamic, toxicogenomic, biotransformation, and resistance mechanisms in the human body. The book begins with a historical review and link to future prospects for chemical carcinogenesis. It discusses major environmental xenobiotics and their risks in inducing cancer, along with content on toxic xenobiotics and their routes of exposure in humans, the role of xenobiotic metabolism in carcinogenesis, and the toxicokinetic and toxicodynamic of xenobiotics in cancer development.\u003c/p\u003e \u003cp\u003eLastly, the book explores current achievements such as using toxicogenomics for predicting the carcinogenicity of xenobiotic substances and the challenges posed by carcinogenic xenobiotic substances when examining preventive methods, diagnosis, and the development of anticancer drugs for specific toxicants.\u003c/p\u003e\u003cul\u003e \u003cli\u003eCovers the exposure and transmission of various toxic xenobiotics substances, including nanomaterials, to humans and their interaction with specific tissues in precipitating the development of cancers\u003c/li\u003e \u003cli\u003eUnravels the toxicokinetic and toxicodynamic processes of toxic xenobiotics in bioaccumulation\u003c/li\u003e \u003cli\u003eExamines the genetic aberrations in cancer genomes by genetic-environmental interactions in carcinogenesis\u003c/li\u003e \u003cli\u003eExplains the biotransformation mechanisms of toxic xenobiotics by gut microbes in humans\u003c/li\u003e\u003c/ul\u003e |
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