\u003cp\u003eIn this issue of \u003ci\u003eCritical Care Nursing Clinics\u003c/i\u003e, Guest Editor May M. Riley brings her considerable expertise to the topic of \u003cb\u003eInfection Challenges in the Critical Care Unit\u003c/b\u003e. Top experts in the field cover key topics such as Implementing an Antimicrobial Stewardship Program, Pulmonary Infections, Including Ventilator-Associated Pneumonia (VAP), Preventing Central Line-Associated Bloodstream Infection (CLABSI), and more.\u003c/p\u003e\u003cul\u003e \u003cli\u003eProvides in-depth, \u003cb\u003eclinical reviews on Infection Challenges in the Critical Care Unit\u003c/b\u003e, providing actionable insights for clinical practice.\u003c/li\u003e \u003cp\u003e \u003cli\u003ePresents the \u003cb\u003elatest information on this timely, focused topic\u003c/b\u003e under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.\u003c/li\u003e \u003cli\u003eContains \u003cb\u003e8 relevant, practice-oriented topics\u003c/b\u003e including Epidemiology of Invasive Fungal Disease; Management of Sepsis; Multidrug-Resistant Candida Species and Candidiasis Infections; Infections in Geriatric Patients; Transmission and Multidrug-Resistant Organisms; and more.\u003c/li\u003e\u003c/ul\u003e