\u003cp\u003eThe realisation that human, animal, viral and bacterial genomes all contain over-representation of higher-order quadruplex structures in regulatory and other pharmacologically-useful regions, has led to a large number of studies aimed at exploiting this findings for therapeutic and diagnostic purposes. Quadruplex-binding small molecules are starting to be evaluated in human clinical trials.\u003c/p\u003e\u003cul\u003e\u003cli\u003eProvides the authority and expertise of leading contributors from an international board of authors\u003c/li\u003e\u003cli\u003ePresents the latest release in the \u003ci\u003eAnnual Reports in Medicinal Chemistry \u003c/i\u003eseries\u003c/li\u003e\u003c/ul\u003e
nl
en