\u003ci\u003e \u003cp\u003eSide Reactions in Peptide Synthesis, \u003c/i\u003ebased on the authorâs academic and industrial experience, and backed by a thorough review of the current literature, provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis. \u003c/p\u003e \u003cp\u003eThis valuable handbook is ideal for research and process chemists working with peptide synthesis in diverse settings across academic, biotech, and pharmaceutical research and development. \u003c/p\u003e \u003cp\u003eWhile peptide chemistry is increasingly prevalent, common side reactions and their causes are often poorly understood or anticipated, causing unnecessary waste of materials and delay. \u003c/p\u003e \u003cp\u003eEach chapter discusses common side reactions through detailed chemical equations, proposed mechanisms (if any), theoretical background, and finally, a variety of possible solutions to avoid or alleviate the specified side reaction. \u003c/p\u003e\u003cul\u003e \u003cli\u003eProvides a systematic examination on how to troubleshoot and minimize the most frequent side reactions in peptide synthesis\u003c/li\u003e \u003cli\u003eGives chemists the background information and the practical tools they need to successfully troubleshoot and improve results\u003c/li\u003e \u003cli\u003eIncludes optimization-oriented analysis of side reactions in peptide synthesis for improved industrial process development in peptidyl API (active pharmaceutical ingredient) production \u003c/li\u003e \u003cli\u003eAnswers the growing, global need for improved, replicable processes to avoid impurities and maintain the integrity of the end product.\u003c/li\u003e \u003cli\u003ePresents a thorough discussion of critical factors in peptide synthesis which are often neglected or underestimated by chemists \u003c/li\u003e \u003cli\u003eCovers solid phase and solution phase methodologies, and provides abundant references for further exploration\u003c/li\u003e\u003c/ul\u003e
nl
en