\u003cp\u003eKeeping abreast of the major strides made in the field of neuropathology, \u003ccite\u003eEssentials of Diagnostic Surgical Neuropathology\u003c/cite\u003e brings out its second edition with the aim of keeping the neuroscience community updated with the new developments in neuropathology.\u003c/p\u003e\u003cp\u003eThis second edition comes close on the heels of the fifth edition of the WHO Classification of Central Nervous System Tumours (WHO CNS5) which was published in 2021. This new edition has retained the concise, point wise format of the earlier edition, making it a handy reference book. While the major changes in this edition are in neoplastic pathology, this book also provides updates in the pathology of non-neoplastic lesions that need surgical intervention.\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eThe highlights of the neoplastic section are:\u003c/strong\u003e\u003cul\u003e\u003cli\u003eDescription of new tumour types and subtypes included in the WHO CNS5\u003c/li\u003e\u003cli\u003eGrading of tumours as per WHO CNS5\u003c/li\u003e\u003cli\u003eRelevant immune profile and diagnostic molecular pathology for each tumour according to WHO CNS5. Essential and desirable diagnostic criteria, as defined by WHO CNS5, in a tabular form at the end\u003c/li\u003e\u003c/ul\u003e\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eThe salient features of the non-neoplastic section include:\u003c/strong\u003e\u003cul\u003e\u003cli\u003eNew section on Therapy-related Neuropathology\u003c/li\u003e\u003cli\u003eRecent classifications of vascular malformations and epilepsy related lesions\u003c/li\u003e\u003cli\u003eNew section on Infectious and Inflammatory Lesions Mimicking Neoplasms\u003c/li\u003e\u003cli\u003eNew chapter on Surgical Pathology of Spinal Dysraphism and Other Neural Tube Defects\u003c/li\u003e\u003cli\u003eAnother important feature includes the addition of a new chapter on techniques viz.\u003c/li\u003e\u003cli\u003eSmears in the Rapid Diagnosis of Central Nervous System Lesions\u003c/li\u003e\u003cli\u003eChallenges in the Interpretation of Stereotactic Biopsies\u003c/li\u003e\u003c/ul\u003e\u003c/p\u003e