[Annotatie]: This is the first work to take a comprehensive look at the application of magnetic resonance (MR) techniques in the diagnosis, follow-up and therapy monitoring of dementing illnesses. Over the years MR has proven to be an extremely valuable method of identifying treatable disorders of dementia at an early stage, which is of great importance when keeping in mind that about 1-6% of the population over the age of 65 suffers from dementing illnesses. The authors present an overview of MR findings in neurodegenerative and vascular disorders leading to dementia. In doing so, they also discuss other diseases that lead to cognitive and/or behavioural deterioration such as infectious-inflammatory disorders, toxic encephalopathies, inborn errors of metabolism of adult onset and post-traumatic, post-radiotherapy and post-chemotherapy conditions. This authoritative, well-written and richly illustrated reference work is indispensable for anybody working in the field. TOC:Introduction. Brain atrophy and normal aging.- MR applications in dementia. MR techniques. Image processing.- Neurodegenerative disorders. Alzheimer's disease. Dementia with Lewy bodies. Frontotemporal lobar degeneration. Dementia with Parkinsonism. Huntington's dementia. Progressive subcortical gliosis. Prion-linked dementias.- Disorders primarily affecting white matter. Viral infections leading to dementia. Inflammatory disorders. Inborn errors of metabolism. Toxic-allergic encephalopathies. Dementia after trauma, irradiation, chemotherapy and infection.- Vascular dementias. Commonly used criteria for vascular dementia. Vascular dementia: MR features of subgroups. Vascular dementias with characteristic clinical course, familial story, pathophysiology and MR pattern. Systemic disorders and cerebrovascular disease. Vasculitis.- Miscellaneous forms of dementia. Normal pressure hydrocephalus and dementia. Intra- and extra-axial tumors and dementia. Idiopathic calcinosis of Fahr.
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